Ulcerative Colitis: A new treatment strategy discovered

A new study discovers that Type I collagen and its daughter peptides is promising in targeting mucosal healing in ulcerative colitis.

Ulcerative colitis is a chronic relapsing form of inflammatory bowel disease that causes inflammation and ulcers in the colon. Symptoms can range from mild to severe with disease onset usually occurring in young adults.

The existing treatment protocol aims at only reducing intestinal inflammation, rather than targeting mucosal ulceration.

In the study, type I collagen and its daughter peptides called collagen hydrolysate, highly popular reconstructive materials for tissue engineering applications, are hypothesized as healing matrices to target the recuperation of internal mucosal ulceration.

The study concludes, Both collagen and collagen hydrolysate treatments showed significant reduction in mucosal damage score and facilitated faster regeneration of damaged mucosa.

Reference material gotten from:
ScienceDirect